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Duromine vs Sibutramine

Duromine and Sibutramine are among the best-known medications to cope with extra weight and to treat obesity. Both these medications provide anorexigenic effect.

  • Duromine
Sibutramine

Duromine drug contains active ingredient Phentermine, known on pharmaceutical market since 1959. Duromine is produced in capsules. Each Duromine capsule contains 15mg, 30g or 40mg of Phentermine.

  • Sibutramine

Sibutramine is the active substance, known on pharmacological market since 1997. Nowadays, Sibutramine is no longer produced and no longer sold in most of the countries (for instance, USA, Canada, EU and Australia).

Main similarities and differences between Duromine and Sibutramine


Clinical trials have shown that the weight loss drug Sibutramine increases the risk of cardiovascular diseases by 15-17%. The TGA has established that the risk caused by Sibutramine is higher than the benefit from its use.

Clinical trials have shown that the weight loss drug Sibutramine increases the risk of cardiovascular diseases by 15-17%. The TGA has established that the risk caused by Sibutramine is higher than the benefit from its use.

Sibutramine is known in Australia under the trademark Ectiva. The weight loss drug Ectiva has been released in form of capsules, containing 10mg or 15mg of Sibutramine Hydrochloride.

Both drugs Duromine and Sibutramine should be used before noon with breakfast and large amount of water. The anti-obesity drugs Duromine and Sibutramine act directly on the patient’s nervous system, reducing hunger feeling. The application of Duromine or Sibutramine will help obese people to reduce at least 5-10% (Duromine can reduce up to 15%) of their body weight.

Just as any other medications, Duromine and Sibutramine can provoke side effects. Duromine drug causes less side effects than Sibutramine, and thus it is available on sale in many countries of the world.

  • Duromine side effects are usually short-term. The most common Duromine side effects are tiredness, insomnia, abdominal pain, hypertension, dizziness, nervousness, nausea, vomiting, euphoria, headache and irritability.
  • During the obesity treatment by means of Sibutramine drug, patient may suffer from anxiety, sweating, dry mouth, headache, nausea, dizziness and constipation. Sibutramine may cause more serious side effects, such as: depression, suicidal thoughts, seizures, high blood pressure and palpitation.

Before you buy Duromine or Sibutramine, you should undergo a medical examination and make sure these drugs are not contraindicated in you. In case they are, Duromine and Sibutramine diet pills must be changed for some alternative weight loss drugs.

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